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Practical Synthesis of Prostratin, DPP, and Their Analogs, Adjuvant Leads Against Latent HIV

Although antiretroviral therapies have been effective in decreasing active viral loads in AIDS patients, the persistence of latent viral reservoirs prevents eradication of the virus. Prostratin and DPP (12-deoxyphorbol-13-phenylacetate) activate the latent virus and thus represent promising adjuvant...

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Hlavní autoři: Wender, Paul A., Kee, Jung-Min, Warrington, Jeffrey M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704988/
https://ncbi.nlm.nih.gov/pubmed/18451298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1154690
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