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The Hippo pathway regulates apical-domain size independently of its growth-control function

The Hippo pathway, identified in Drosophila and conserved in vertebrates, regulates tissue growth by promoting cell cycle exit and apoptosis. In addition to their well-characterised overproliferation phenotype, adult Drosophila epithelial cells mutant for the kinases Hippo and Warts have hypertrophi...

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Autors principals: Genevet, Alice, Polesello, Cédric, Blight, Ken, Robertson, Francesca, Collinson, Lucy M., Pichaud, Franck, Tapon, Nicolas
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704876/
https://ncbi.nlm.nih.gov/pubmed/19531586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.041806
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