The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration

Intestinal stem cells (ISCs) in the adult Drosophila midgut proliferate to self-renew and to produce differentiating daughter cells that replace those lost as part of normal gut function. Intestinal stress induces the activation of Upd/Jak/Stat signalling, which promotes intestinal regeneration by i...

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Bibliographic Details
Main Authors: Shaw, Rachael L., Kohlmaier, Alexander, Polesello, Cédric, Veelken, Cornelia, Edgar, Bruce A., Tapon, Nicolas
Format: Artigo
Language:Inglês
Published: Company of Biologists 2010
Subjects:
Development and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990206/
https://ncbi.nlm.nih.gov/pubmed/21068063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.052506
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