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Histone Acetyltransferase CBP Is Vital To Demarcate Conventional and Innate CD8(+) T-Cell Development

Defining the chromatin modifications and transcriptional mechanisms that direct the development of different T-cell lineages is a major challenge in immunology. The transcriptional coactivators CREB binding protein (CBP) and the closely related p300, which comprise the KAT3 family of histone/protein...

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Autores principales: Fukuyama, Tomofusa, Kasper, Lawryn H., Boussouar, Fayçal, Jeevan, Trushar, van Deursen, Jan, Brindle, Paul K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704754/
https://ncbi.nlm.nih.gov/pubmed/19433445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01598-08
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