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NADPH Oxidase 1 Controls the Persistence of Directed Cell Migration by a Rho-Dependent Switch of α2/α3 Integrins

NADPH oxidase 1 (Nox1) is expressed mainly in colon epithelial cells and produces superoxide ions as a primary function. We showed that Nox1 knockdown inhibits directional persistence of migration on collagen I. This paper dissects the mechanism by which Nox1 affects the direction of colonic epithel...

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Bibliografski detalji
Glavni autori: Sadok, Amine, Pierres, Anne, Dahan, Laetitia, Prévôt, Charles, Lehmann, Maxime, Kovacic, Hervé
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704751/
https://ncbi.nlm.nih.gov/pubmed/19451223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01199-08
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