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In Vitro Chemosensitization of Plasmodium falciparum to Antimalarials by Verapamil and Probenecid
We tested the effect of probenecid and verapamil in chemosensitizing Plasmodium falciparum to 14 antimalarials using the multidrug-resistant strain V1S and the drug-sensitive 3D7. Verapamil chemosensitizes V1S to quinine and chloroquine. Interestingly, probenecid profoundly chemosensitizes V1S to pi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704629/ https://ncbi.nlm.nih.gov/pubmed/19364853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01689-08 |
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