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In Vitro Chemosensitization of Plasmodium falciparum to Antimalarials by Verapamil and Probenecid

We tested the effect of probenecid and verapamil in chemosensitizing Plasmodium falciparum to 14 antimalarials using the multidrug-resistant strain V1S and the drug-sensitive 3D7. Verapamil chemosensitizes V1S to quinine and chloroquine. Interestingly, probenecid profoundly chemosensitizes V1S to pi...

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Bibliografiske detaljer
Main Authors: Masseno, Victor, Muriithi, Steven, Nzila, Alexis
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704629/
https://ncbi.nlm.nih.gov/pubmed/19364853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01689-08
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