Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress

The MerTK plays several important roles in normal macrophage physiology, including regulation of cytokine secretion and clearance of apoptotic cells. Mer signaling in other cell types, including malignant cells that ectopically overexpress the RTK, leads to downstream prosurvival pathway activation....

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Main Authors: Anwar, Adil, Keating, Amy K., Joung, David, Sather, Susan, Kim, Grace K., Sawczyn, Kelly K., Brandão, Luis, Henson, Peter M., Graham, Douglas K.
Formato: Artigo
Idioma:Inglês
Publicado: The Society for Leukocyte Biology 2009
Assuntos:
Receptors, Signal Transduction, & Genes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704622/
https://ncbi.nlm.nih.gov/pubmed/19386698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/JLB.0608334
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