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The Endocannabinoid Anandamide is a Substrate for the Human Polymorphic Cytochrome P450 2D6

Members of the cytochrome P450 (CYP) family of drug metabolizing enzymes are present in the human brain and they may have important roles in the oxidation of endogenous substrates. The polymorphic CYP2D6 is one of the major brain CYP isoforms and has been implicated in neurodegeneration, psychosis,...

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Autors principals: Snider, Natasha T., Sikora, Matthew J., Sridar, Chitra, Feuerstein, Thomas J., Rae, James M., Hollenberg, Paul F.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704579/
https://ncbi.nlm.nih.gov/pubmed/18698000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.141796
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