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Contribution of the Conserved Amino Acids of the Melanocortin-4 Receptor in D-[Nle(4),Phe(7)]-α-Melanocyte-stimulating Hormone Binding and Signaling(□S)
Melanocortin 4 receptor (MC4R) plays an important role in the regulation of food intake and body weight. To determine the molecular basis of human MC4R (hMC4R) responsible for α-melanocortin-stimulating hormone (α-MSH) binding, in this study, we utilized both receptor domain exchange and site-direct...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704061/ https://ncbi.nlm.nih.gov/pubmed/17545153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M702285200 |
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