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The plasticity of a translation arrest motif yields insights into nascent polypeptide recognition inside the ribosome tunnel
The recognition of a C-terminal motif in E. coli SecM ((150)FXXXXWIXXXXGIRAGP(166)) inside the ribosome tunnel causes translation arrest, but the mechanism of recognition is unknown. While single mutations in this motif impair recognition, we demonstrate that new arrest-inducing peptides can be crea...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704006/ https://ncbi.nlm.nih.gov/pubmed/19394297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.04.002 |
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