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Path of Nascent Polypeptide in Exit Tunnel Revealed by Molecular Dynamics Simulation of Ribosome
Molecular dynamics simulations were carried out on Thermus thermophilus 70S ribosome with and without a nascent polypeptide inside the exit tunnel. Modeling of the polypeptide in the tunnel revealed two possible paths: one over Arg(92) of L22 and one under (from the viewpoint of 50S on top of 30S)....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2599861/ https://ncbi.nlm.nih.gov/pubmed/18936244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.134890 |
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