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A MULTISCALE APPROACH TO SAMPLING NASCENT PEPTIDE CHAINS IN THE RIBOSOMAL EXIT TUNNEL

We present a new multiscale method that combines all-atom molecular dynamics with coarse-grained sampling, towards the aim of bridging two levels of physiology: the atomic scale of protein side chains and small molecules, and the huge scale of macromolecular complexes like the ribosome. Our approach...

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Bibliographic Details
Published in:Pac Symp Biocomput
Main Authors: Voelz, V. A., Petrone, P., Pande, V. S.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423764/
https://ncbi.nlm.nih.gov/pubmed/19209713
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