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C-Reactive Protein Impairs Coronary Arteriolar Dilation to Prostacyclin Synthase Activation: Role of Peroxynitrite

Endothelium-derived vasodilators, i.e., nitric oxide (NO), prostacyclin (PGI(2)) and prostaglandin E(2) (PGE(2)), play important roles in maintaining cardiovascular homeostasis. C-reactive protein (CRP), a biomarker of inflammation and cardiovascular disease, has been shown to inhibit NO-mediated va...

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Detalhes bibliográficos
Main Authors: Hein, Travis W., Qamirani, Erion, Ren, Yi, Kuo, Lih
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703687/
https://ncbi.nlm.nih.gov/pubmed/19410579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.04.015
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