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Endothelin-1 Impairs Coronary Arteriolar Dilation: Role of p38 Kinase-mediated Superoxide Production from NADPH Oxidase

Elevated levels of endothelin-1 (ET-1), a potent vasoactive peptide, are implicated as a risk factor for cardiovascular diseases by exerting vasoconstriction. The aim of this study was to address whether ET-1, at sub-vasomotor concentrations, elicits adverse effects on coronary microvascular functio...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Thengchaisri, Naris, Hein, Travis W., Ren, Yi, Kuo, Lih
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558216/
https://ncbi.nlm.nih.gov/pubmed/26211713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.07.014
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