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Persistent Oxidative Stress Due to Absence of Uncoupling Protein 2 Associated with Impaired Pancreatic β-Cell Function

Uncoupling protein (UCP) 2 is a widely expressed mitochondrial protein whose precise function is still unclear but has been linked to mitochondria-derived reactive oxygen species production. Thus, the chronic absence of UCP2 has the potential to promote persistent reactive oxygen species accumulatio...

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Détails bibliographiques
Auteurs principaux: Pi, Jingbo, Bai, Yushi, Daniel, Kiefer W., Liu, Dianxin, Lyght, Otis, Edelstein, Diane, Brownlee, Michael, Corkey, Barbara E., Collins, Sheila
Format: Artigo
Langue:Inglês
Publié: The Endocrine Society 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703519/
https://ncbi.nlm.nih.gov/pubmed/19246534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1642
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