Persistent Nuclear Factor-κB Activation in Ucp2−/− Mice Leads to Enhanced Nitric Oxide and Inflammatory Cytokine Production

One of the phenotypes of mice with targeted disruption of the uncoupling protein-2 gene (Ucp2−/−) is greater macrophage phagocytic activity and free radical production, resulting in a striking resistance to infectious microorganisms. In this study, the molecular mechanisms of this enhanced immune re...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Bai, Yushi, Onuma, Hiroki, Bai, Xu, Medvedev, Alexander V., Misukonis, Mary, Weinberg, J. Brice, Cao, Wenhong, Robidoux, Jacques, Floering, Lisa M., Daniel, Kiefer W., Collins, Sheila
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1382174/
https://ncbi.nlm.nih.gov/pubmed/15757894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M500566200
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge