p38 Mitogen-Activated Protein Kinase Is the Central Regulator of Cyclic AMP-Dependent Transcription of the Brown Fat Uncoupling Protein 1 Gene

It is well established that catecholamine-stimulated thermogenesis in brown fat requires β-adrenergic elevations in cyclic AMP (cAMP) to increase expression of the uncoupling protein 1 (UCP1) gene. However, little is known about the downstream components of the signaling cascade or the relevant tran...

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Detalhes bibliográficos
Main Authors: Cao, Wenhong, Daniel, Kiefer W., Robidoux, Jacques, Puigserver, Pere, Medvedev, Alexander V., Bai, Xu, Floering, Lisa M., Spiegelman, Bruce M., Collins, Sheila
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371122/
https://ncbi.nlm.nih.gov/pubmed/15024092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.7.3057-3067.2004
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