Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

The protein kinase Chk2, the mammalian homolog of the budding yeast Rad53 and fission yeast Cds1 checkpoint kinases, is phosphorylated and activated in response to DNA damage by ionizing radiation (IR), UV irradiation, and replication blocks by hydroxyurea (HU). Phosphorylation and activation of Chk...

全面介紹

書目詳細資料

發表在:	Proc Natl Acad Sci U S A
Principais autores:	Matsuoka, Shuhei, Rotman, Galit, Ogawa, Akira, Shiloh, Yosef, Tamai, Katsuyuki, Elledge, Stephen J.
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 2000
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27034/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10973490/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.190030497
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!