Telomerase-pulsed dendritic cells: preclinical results and outcome of a clinical phase I/II trial in patients with metastatic renal cell carcinoma

Objective: Therapeutic vaccination with dendritic cells (DC) showed promising results in first clinical trials in cases of metastatic renal cell carcinoma (RCC). Human telomerase reverse transcriptase (hTERT) could be a potential target because it is detectable in more than 85% of human tumors inclu...

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Hlavní autoři: Märten, Angela, Sievers, Elisabeth, Albers, Peter, Müller, Stefan, Franchy, Christian, von Ruecker, Alexander, Strunk, Holger, Schild, Hans Heinz, Schmiedel, Alexandra, Sommer, Thorsten, Sauerbruch, Tilman, Schmidt-Wolf, Ingo G.H.
Médium: Artigo
Jazyk:Inglês
Vydáno: German Medical Science 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703216/
https://ncbi.nlm.nih.gov/pubmed/19675693
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