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Targeting TNFα Rapidly Reduces Density of Dendritic Cells and Macrophages in Psoriatic Plaques with Restoration of Epidermal Keratinocyte Differentiation
BACKGROUND: The cytokine network theory for psoriasis postulates a key role for TNFa in mediating inflammation and altered epidermal differentiation. OBJECTIVE: This study defines responses following administration of adalimumab, a TNFα inhibitor, in pre-psoriatic skin (PN) and lesional psoriatic pl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703191/ https://ncbi.nlm.nih.gov/pubmed/17689932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2007.06.006 |
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