Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared with normal skin.

Previously we observed that hyperplastic epidermal keratinocytes characteristic of psoriasis had abundant amounts of the cell survival protein Bcl-xL; however, whether this overexpression correlated with enhanced survival was unclear because the majority of epidermal cells possess nuclei that are po...

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Bibliographic Details
Main Authors: Wrone-Smith, T., Mitra, R. S., Thompson, C. B., Jasty, R., Castle, V. P., Nickoloff, B. J.
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858068/
https://ncbi.nlm.nih.gov/pubmed/9358758
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