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Accessibility of Chromosomal Recombination Breaks in Nuclei of Wild-type and DNA-PKcs-Deficient cells

V(D)J recombination is a highly regulated process, proceeding from a site-specific cleavage to an imprecise end joining. After the DNA excision catalyzed by the recombinase encoded by Recombination Activating Genes 1 and 2 (RAG1/2), newly generated recombination ends are believed held by a post-clea...

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Detalhes bibliográficos
Main Authors: Franco, Daniel, Chang, Yung
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703179/
https://ncbi.nlm.nih.gov/pubmed/19395319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.03.007
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