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Crystal structure of the histo-aspartic protease (HAP) from Plasmodium falciparum
The structures of recombinant histo-aspartic protease (HAP) from malaria-causing parasite Plasmodium falciparum, as apoenzyme and in complex with two inhibitors, pepstatin A and KNI-10006, were solved at 2.5, 3.3, and 3.05 Å resolution, respectively. In the apoenzyme crystals HAP forms a tight dimer...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702178/ https://ncbi.nlm.nih.gov/pubmed/19285084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.011 |
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