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Nickel Mobilizes Intracellular Zinc to Induce Metallothionein in Human Airway Epithelial Cells

We recently reported that induction of metallothionein (MT) was critical in limiting nickel (Ni)-induced lung injury in intact mice. Nonetheless, the mechanism by which Ni induces MT expression is unclear. We hypothesized that the ability of Ni to mobilize zinc (Zn) may contribute to such regulation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nemec, Antonia A., Leikauf, George D., Pitt, Bruce R., Wasserloos, Karla J., Barchowsky, Aaron
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701961/
https://ncbi.nlm.nih.gov/pubmed/19097988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0409OC
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