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Single Nucleotide Changes in the Human Iγ1 and Iγ4 Promoters Underlie Different Transcriptional Responses to CD40

Analysis of subclass-specific germline transcription (GLT) in activated peripheral B cells revealed a highly biased expression pattern of the four Iγ transcripts to signals through CD40 and IL-4. This difference was most pronounced when comparing the profile of Iγ1 and Iγ4 transcripts and not expect...

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Bibliografiske detaljer
Main Authors: Sinquett, Frank L., Dryer, Rebecca L., Marcelli, Valentina, Batheja, Ameesha, Covey, Lori R.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701896/
https://ncbi.nlm.nih.gov/pubmed/19201872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802700
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