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A Dual-Acceptor Time-Resolved Föster Resonance Energy Transfer Assay for Simultaneous Determination of Thyroid Hormone Regulation of Corepressor and Coactivator Binding to the Thyroid Hormone Receptor: Mimicking the Cellular Context of Thyroid Hormone Action
Previously, we reported the development of two in vitro time-resolved Föster energy transfer (tr-FRET) based assays for evaluating the potency and efficacy of different ligands of thyroid hormone receptor (TR) for regulating the recruitment of coregulators; we could measure independently, in separat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701686/ https://ncbi.nlm.nih.gov/pubmed/19111515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.11.039 |
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