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Zic-associated holoprosencephaly: zebrafish Zic1 controls midline formation and forebrain patterning by regulating Nodal, Hedgehog, and retinoic acid signaling

Holoprosencephaly (HPE) is the most frequently observed human embryonic forebrain defect. Recent evidence indicates that the two major forms of HPE, classic HPE and midline interhemispheric (MIH) HPE, are elicited by two different mechanisms. The only gene known to be associated with both forms of H...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Maurus, Daniel, Harris, William A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701571/
https://ncbi.nlm.nih.gov/pubmed/19528322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.517009
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