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Zic-associated holoprosencephaly: zebrafish Zic1 controls midline formation and forebrain patterning by regulating Nodal, Hedgehog, and retinoic acid signaling
Holoprosencephaly (HPE) is the most frequently observed human embryonic forebrain defect. Recent evidence indicates that the two major forms of HPE, classic HPE and midline interhemispheric (MIH) HPE, are elicited by two different mechanisms. The only gene known to be associated with both forms of H...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701571/ https://ncbi.nlm.nih.gov/pubmed/19528322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.517009 |
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