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Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression

Holoprosencephaly (HPE) is the most common congenital malformation of the forebrain in human. Several genes with essential roles during forebrain development have been identified because they cause HPE when mutated. Among these are genes that encode the secreted growth factor Sonic hedgehog (Shh) an...

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Detalhes bibliográficos
Main Authors: Sanek, Nicholas A., Taylor, Aaron A., Nyholm, Molly K., Grinblat, Yevgenya
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766342/
https://ncbi.nlm.nih.gov/pubmed/19855021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.037820
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