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MAPK p38 Regulates Transcriptional Activity of NF-κB in Primary Human Astrocytes via Acetylation of p65

MAPK-p38 plays an important role in inflammation. Several studies have shown that blocking p38 activity attenuates the transcriptional activity of the proinflammatory transcription factor NF-κB without altering its DNA-binding activity. We have also observed that blocking p38 in human primary astroc...

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Bibliografiske detaljer
Main Authors: Saha, Ramendra N., Jana, Malabendu, Pahan, Kalipada
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701546/
https://ncbi.nlm.nih.gov/pubmed/17982102
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