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Fluorescence Lifetime of Actin in the FHC Transgenic Heart
Clinical studies have revealed that the D166V mutation in the ventricular myosin regulatory light chain (RLC) can cause a malignant phenotype of familial hypertrophic cardiomyopathy (FHC). It has been proposed that RLC induced FHC in the heart originates at the level of the myosin cross-bridge due t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701482/ https://ncbi.nlm.nih.gov/pubmed/19159226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801629d |
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