Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23

The most consistent finding derived from the WTCCC GWAS for rheumatoid arthritis (RA) was association to a SNP at 6q23. We performed a fine-mapping of the region in order to search the 6q23 region for additional disease variants. 3962 RA patients and 3531 healthy controls were included in the study....

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Autori principali: Orozco, Gisela, Hinks, Anne, Eyre, Steve, Ke, Xiayi, Gibbons, Laura J., Bowes, John, Flynn, Edward, Martin, Paul, Wilson, Anthony G., Bax, Deborah E., Morgan, Ann W., Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M., Wordsworth, Paul, Harrison, Pille, Thomson, Wendy, Barton, Anne, Worthington, Jane
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
Soggetti:
Association Studies Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701332/
https://ncbi.nlm.nih.gov/pubmed/19417005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp193
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