Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23

The most consistent finding derived from the WTCCC GWAS for rheumatoid arthritis (RA) was association to a SNP at 6q23. We performed a fine-mapping of the region in order to search the 6q23 region for additional disease variants. 3962 RA patients and 3531 healthy controls were included in the study....

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Detalhes bibliográficos
Main Authors: Orozco, Gisela, Hinks, Anne, Eyre, Steve, Ke, Xiayi, Gibbons, Laura J., Bowes, John, Flynn, Edward, Martin, Paul, Wilson, Anthony G., Bax, Deborah E., Morgan, Ann W., Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M., Wordsworth, Paul, Harrison, Pille, Thomson, Wendy, Barton, Anne, Worthington, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701332/
https://ncbi.nlm.nih.gov/pubmed/19417005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp193
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