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Binding Modes of CCR5-targetting HIV Entry Inhibitors: Partial and Full Antagonists
Since the CC-chemokine receptor 5 (CCR5) was identified as a major coreceptor for human immunodeficiency virus type 1 (HIV-1) entry into a host cell, CCR5-targetting HIV entry inhibitors have been developed and some of them are currently in clinical trials. Most of these inhibitors also inhibit the...
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2007
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701198/ https://ncbi.nlm.nih.gov/pubmed/18249144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2007.12.003 |
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