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Binding Modes of CCR5-targetting HIV Entry Inhibitors: Partial and Full Antagonists

Since the CC-chemokine receptor 5 (CCR5) was identified as a major coreceptor for human immunodeficiency virus type 1 (HIV-1) entry into a host cell, CCR5-targetting HIV entry inhibitors have been developed and some of them are currently in clinical trials. Most of these inhibitors also inhibit the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Ting, Duan, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701198/
https://ncbi.nlm.nih.gov/pubmed/18249144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2007.12.003
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