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LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis
TAL1 is a critical transcription factor required for hematopoiesis. However, perturbation of its activity often leads to T cell leukemia. Whether and how its transcriptional activities are regulated during hematopoiesis remains to be addressed. Here, we show that TAL1 is associated with histone deme...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700898/ https://ncbi.nlm.nih.gov/pubmed/19497860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900437106 |
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