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Dynamic interaction between TAL1 oncoprotein and LSD1 regulates TAL1 function in hematopoiesis and leukemogenesis

TAL1/SCL is a hematopoietic specific oncogene and its activity is regulated by associated transcriptional coactivators and corepressors. Dysregulation of TAL1 activity has been associated with T cell leukemogenesis. However, it remains unclear how the interactions between TAL1 and corepressors versu...

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Main Authors: Li, Ying, Deng, Changwang, Hu, Xin, Patel, Bhavita, Fu, Xueqi, Qiu, Yi, Brand, Marjorie, Zhao, Keji, Huang, Suming
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510314/
https://ncbi.nlm.nih.gov/pubmed/22310283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.8
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