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Dynamic interaction between TAL1 oncoprotein and LSD1 regulates TAL1 function in hematopoiesis and leukemogenesis
TAL1/SCL is a hematopoietic specific oncogene and its activity is regulated by associated transcriptional coactivators and corepressors. Dysregulation of TAL1 activity has been associated with T cell leukemogenesis. However, it remains unclear how the interactions between TAL1 and corepressors versu...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510314/ https://ncbi.nlm.nih.gov/pubmed/22310283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.8 |
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