Combined antiviral activity of interferon-α and RNA interference directed against hepatitis C without affecting vector delivery and gene silencing

The current standard interferon-alpha (IFN-α)-based therapy for chronic hepatitis C virus (HCV) infection is only effective in approximately half of the patients, prompting the need for alternative treatments. RNA interference (RNAi) represents novel approach to combat HCV by sequence-specific targe...

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Detalhes bibliográficos
Main Authors: Pan, Qiuwei, Henry, Scot D., Metselaar, Herold J., Scholte, Bob, Kwekkeboom, Jaap, Tilanus, Hugo W., Janssen, Harry L. A., van der Laan, Luc J. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700866/
https://ncbi.nlm.nih.gov/pubmed/19404587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0470-3
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