Mycophenolic acid is a potent inhibitor of the expression of tumour necrosis factor- and tumour necrosis factor-receptor superfamily costimulatory molecules

The tumour necrosis factor (TNF) ligands CD154, CD70 and TNF receptors CD134 and CD137 are all involved in allograft rejection. Because these molecules are not present on resting T cells, we investigated whether immunosuppressive drugs could inhibit their induction. Expression was induced in vitro o...

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Detalhes bibliográficos
Main Authors: Van Rijen, Miranda M L, Metselaar, Herold J, Hommes, Martijn, Ijzermans, Jan N M, Tilanus, Hugo W, Kwekkeboom, Jaap
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782937/
https://ncbi.nlm.nih.gov/pubmed/12709024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01635.x
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