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Mycophenolic acid is a potent inhibitor of the expression of tumour necrosis factor- and tumour necrosis factor-receptor superfamily costimulatory molecules

The tumour necrosis factor (TNF) ligands CD154, CD70 and TNF receptors CD134 and CD137 are all involved in allograft rejection. Because these molecules are not present on resting T cells, we investigated whether immunosuppressive drugs could inhibit their induction. Expression was induced in vitro o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Van Rijen, Miranda M L, Metselaar, Herold J, Hommes, Martijn, Ijzermans, Jan N M, Tilanus, Hugo W, Kwekkeboom, Jaap
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782937/
https://ncbi.nlm.nih.gov/pubmed/12709024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01635.x
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