Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase
BACKGROUND: Bloom syndrome is one of the most cancer-predisposing disorders and is characterized by genomic instability and a high frequency of sister chromatid exchange. The disorder is caused by loss of function of a 3' to 5' RecQ DNA helicase, BLM. The exact role of BLM in maintaining genomic int...
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| Udgivet i: | BMC Cell Biol |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC270065/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14577841/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-4-15 |
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