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Regulation of T cell-dendritic cell interactions by IL-7 governs T-cell activation and homeostasis

Interleukin-7 (IL-7) plays a central role in the homeostasis of the T-cell compartment by regulating T-cell survival and proliferation. Whether IL-7 can influence T-cell receptor (TCR) signaling in T cells remains controversial. Here, using IL-7–deficient hosts and TCR-transgenic T cells that condit...

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Main Authors: Saini, Manoj, Pearson, Claire, Seddon, Benedict
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700319/
https://ncbi.nlm.nih.gov/pubmed/19357399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-192252
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