Dendritic cells drive memory CD8 T-cell homeostasis via IL-15 transpresentation

Interleukin-15 (IL-15) is crucial for the development of naive and memory CD8 T cells and is delivered through a mechanism called transpresentation. Previous studies showed that memory CD8 T cells require IL-15 transpresentation by an as yet unknown cell of hematopoietic origin. We hypothesized that...

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Autori principali: Stonier, Spencer W., Ma, Lisa J., Castillo, Eliseo F., Schluns, Kimberly S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
Soggetti:
Immunobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597127/
https://ncbi.nlm.nih.gov/pubmed/18812469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-156307
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