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Intragraft Selection of the T Cell Receptor Repertoire by Class I MHC Sequences in Tolerant Recipients

BACKGROUND: Allograft tolerance of ACI (RT1(a)) recipients to WF (RT1(u)) hearts can be induced by allochimeric class I MHC molecules containing donor-type (RT1A(u)) immunogenic epitopes displayed on recipient-type (RT1A(a)) sequences. Here, we sought the mechanisms by which allochimeric sequences m...

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Main Authors: Liu, Dahai, Shen, Xiu-Da, Zhai, Yuan, Lam, Wengsi, Liao, Jingying, Busuttil, Ronald W., Ghobrial, Rafik M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700265/
https://ncbi.nlm.nih.gov/pubmed/19562081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006076
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