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A functional analysis of PCNA-binding peptides derived from protein sequence, interaction screening and rational design

PCNA has no intrinsic enzymatic function, but functions as a sliding platform to mediate protein interactions with the DNA strand. Many proteins interact with PCNA through a small conserved motif with consensus QxxLxxFF. This work uses S. pombe and human cells to analyse the function of PCNA-binding...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखक: Warbrick, Emma
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2006
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699888/
https://ncbi.nlm.nih.gov/pubmed/16407840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209320
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