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Targeting protein–protein interactions by rational design: mimicry of protein surfaces
Protein–protein interactions play key roles in a range of biological processes, and are therefore important targets for the design of novel therapeutics. Unlike in the design of enzyme active site inhibitors, the disruption of protein–protein interactions is far more challenging, due to such factors...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1578744/ https://ncbi.nlm.nih.gov/pubmed/16849232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2006.0115 |
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