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Targeting protein–protein interactions by rational design: mimicry of protein surfaces

Protein–protein interactions play key roles in a range of biological processes, and are therefore important targets for the design of novel therapeutics. Unlike in the design of enzyme active site inhibitors, the disruption of protein–protein interactions is far more challenging, due to such factors...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Fletcher, Steven, Hamilton, Andrew D
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Royal Society 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578744/
https://ncbi.nlm.nih.gov/pubmed/16849232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2006.0115
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