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The charge-dipole pocket: a defining feature of signaling pathway GTPase on-off switches

Ras-like GTPases function as on-off switches in intracellular signaling pathways. Their on- or off-state is communicated through conformational changes in the so-called switch I and II regions. It is commonly believed that the distinguishing molecular features of these GTPases are well known. Here,...

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Detalhes bibliográficos
Autor principal: Neuwald, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699579/
https://ncbi.nlm.nih.gov/pubmed/19427324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.05.001
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