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The charge-dipole pocket: a defining feature of signaling pathway GTPase on-off switches
Ras-like GTPases function as on-off switches in intracellular signaling pathways. Their on- or off-state is communicated through conformational changes in the so-called switch I and II regions. It is commonly believed that the distinguishing molecular features of these GTPases are well known. Here,...
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Format: | Artigo |
Język: | Inglês |
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2009
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699579/ https://ncbi.nlm.nih.gov/pubmed/19427324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.05.001 |
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