Systemic IFNα drives kidney nephritis in B6.Sle123 mice

The impact of IFNα secretion on disease progression was assessed by comparing phenotypic changes in the lupus-prone B6.Sle1Sle2Sle3 (B6.Sle123) strain and the parental B6 congenic partner using an adenovirus expression vector containing a recombinant IFNα gene cassette (IFN-ADV). A comprehensive com...

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Hauptverfasser: Fairhurst, Anna-Marie, Mathian, Alexis, Connolly, John E, Wang, Andrew, Gray, Hillery F, George, Tiffany A, Boudreaux, Christopher D, Zhou, Xin J, Li, Quan-Zhen, Koutouzov, Sophie, Banchereau, Jacques, Wakeland, Edward K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699327/
https://ncbi.nlm.nih.gov/pubmed/18506882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200837925
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