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N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic

N-glycosylation, a common cotranslational modification, is thought to be critical for plasma membrane expression of glycoproteins by enhancing protein folding, trafficking, and stability through targeting them to the ER folding cycles via lectin-like chaperones. In this study, we show that N-glycans...

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Hlavní autoři: Glozman, Rina, Okiyoneda, Tsukasa, Mulvihill, Cory M., Rini, James M., Barriere, Herve, Lukacs, Gergely L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699153/
https://ncbi.nlm.nih.gov/pubmed/19307599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200808124
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