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N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic

N-glycosylation, a common cotranslational modification, is thought to be critical for plasma membrane expression of glycoproteins by enhancing protein folding, trafficking, and stability through targeting them to the ER folding cycles via lectin-like chaperones. In this study, we show that N-glycans...

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Detalhes bibliográficos
Main Authors: Glozman, Rina, Okiyoneda, Tsukasa, Mulvihill, Cory M., Rini, James M., Barriere, Herve, Lukacs, Gergely L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699153/
https://ncbi.nlm.nih.gov/pubmed/19307599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200808124
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