A Systems Immunology Approach to the Host-Tumor Interaction: Large-Scale Patterns of Natural Autoantibodies Distinguish Healthy and Tumor-Bearing Mice

Traditionally, immunology has considered a meaningful antibody response to be marked by large amounts of high-affinity antibodies reactive with the specific inciting antigen; the detection of small amounts of low-affinity antibodies binding to seemingly unrelated antigens has been considered to be b...

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Main Authors: Merbl, Yifat, Itzchak, Royi, Vider-Shalit, Tal, Louzoun, Yoram, Quintana, Francisco J., Vadai, Ezra, Eisenbach, Lea, Cohen, Irun R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699142/
https://ncbi.nlm.nih.gov/pubmed/19557135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006053
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